In modern geroscience, Epithalon (1) is regarded as the cornerstone for studying the reversal of cellular senescence. Structurally defined as the Ala-Glu-Asp-Gly (AEDG) peptide sequence (2), this ultra-short chain consists of four amino acids that demonstrate a remarkable ability to penetrate the cell nucleus. For institutions focused on lyophilized Epithalon 10mg for laboratory research (3), Mile High Compounds provides a high-stability formulation designed to maintain biological activity during long-term epigenetic mapping.
Mechanism of Action: The Epigenetic Clock Reset
Developed as a synthetic Epithalamin pineal gland fraction (4), this molecule mimics the bioregulatory effects of the natural polypeptide complex isolated from bovine pineal glands. Its primary function in research is acting as an hTERT-activating epigenetic regulator (5). By binding to specific promoter regions of the telomerase reverse transcriptase gene, it induces the elongation of protective chromosomal caps. This makes it a uniquely effective telomere-elongating pineal tetrapeptide (6) for experiments investigating the Hayflick limit and the restoration of youthful protein synthesis in aging cellular models.
Integrity and 2026 Analytical Standards
At Mile High Compounds, we honor the legacy of this Khavinson-derived geroprotective molecule (7) by adhering to the most stringent production standards. Every batch is verified via HPLC and Mass Spectrometry to exceed 99% purity. We provide full access to 2026 batch-specific COAs, ensuring that your data regarding circadian rhythm restoration and antioxidant enzyme upregulation (such as SOD and Catalase) is supported by the highest-grade materials available.
Specifications & Storage
Sequence: Alanine-Glutamate-Asparagine-Glycine
Molecular Weight: 390.35 g/mol
Appearance: Sterile-lyophilized white powder
Storage: Store at -20°C for long-term stability; highly stable in lyophilized form but protect from direct UV light.
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Disclaimer: This compound is sold for in vitro research and educational purposes only. It has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. All buyers must be authorized research personnel or institutions.
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